سوابق علمی و پژوهشی - دانشگاه علوم پزشکی فسا

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M H Afsarian
سید محمد حسین افسریان
(M H Afsarian)
دکتری تخصصی
دانشکده پزشکی, گروه میکروب شناسی
afsariyan@gmail.com

جستجو رزومه

مقاله ها

Seyedeh Mahdieh Hashemi, Hamid Badali, Mohammad Ali Faramarzi, Nasrin Samadi, Mohammad Hosein Afsarian, Hamid Irannejad, Saeed Emami, Date:2015/2/1
AuthorsSeyedeh Mahdieh Hashemi, Hamid Badali, Mohammad Ali Faramarzi, Nasrin Samadi, Mohammad Hosein Afsarian, Hamid Irannejad, Saeed Emami
Date2015/2/1
Volume19
ISSUE1
Page(s)15-27
PublisherSpringer International Publishing
DescriptionAbstract A series of new triazole alcohol antifungals were designed by replacing one of the rntriazolyl moiety from fluconazole with a distinct 4-amino-3-mercapto-1, 2, 4-triazole motif, rnwhich is found in some antimicrobial agents. The antimicrobial susceptibility testing of target rncompounds demonstrated that the direct analogs of fluconazole (difluorophenethyl-triazoles) rnwere less active against fungi, while compound 10h containing dichloro substitutions on rnboth phenyl rings of the molecule had potent activity against yeasts including Candida ...