Roghayeh Shahbazi, Makan Cheraghpour, Reza Homayounfar, Maryam Nazari, Javad Nasrollahzadeh, Sayed Hossein Davoodi, Date:2015/11/15
| Authors | Roghayeh Shahbazi, Makan Cheraghpour, Reza Homayounfar, Maryam Nazari, Javad Nasrollahzadeh, Sayed Hossein Davoodi | |
| Date | 2015/11/15 | |
| Publisher | Medknow Publications | |
| Description | Context: It has been shown that hesperidin induces apoptosis in NALM-6 cells through rninhibition of nuclear factor-kappa B (NF-kB) activation. Aims: To investigate the effect of rnhesperidin on inhibition of NF-kB activation through blocking phosphoinositide 3-kinase rn(PI3K)/Akt pathway as a main target in cancer treatment, in NALM-6 cells. Materials and rnMethods: NALM-6 cells were incubated with two concentrations of hesperidin (25, 50 mM) in rnthe presence or absence of insulin (100 nM), as a potent activator of Akt. The cytotoxic ... | |
