سوابق علمی و پژوهشی - دانشگاه علوم پزشکی فسا

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Mojtaba Farjam
مجتبی فرجام
(Mojtaba Farjam)
دكتري تخصصي PhD
دانشکده پزشکی, گروه فارماکولوژی
farjam@fums.ac.ir

جستجو رزومه

مقاله ها

Mojtaba Farjam, Faegheh Baha'addini Beigi Zarandi, Shirin Farjadian, Bita Geramizadeh, Ali Reza Nikseresht, Mohammad Reza Panjehshahin, Date:2014
AuthorsMojtaba Farjam, Faegheh Baha'addini Beigi Zarandi, Shirin Farjadian, Bita Geramizadeh, Ali Reza Nikseresht, Mohammad Reza Panjehshahin
Date2014
Volume13
ISSUE2
Page(s)695
PublisherShahid Beheshti University of Medical Sciences
DescriptionAbstract Neurodegeneration is the pathophysiological basis for permanent neurological rndisabilities in multiple sclerosis (MS); thus neuroprotection is emerging as a therapeutic rnapproach in MS research. Modulation of excitotoxicity by inhibition of NMDARs has been rnsuggested for neuroprotection, but selective antagonisation of the NR2B subtype of these rnreceptors, a subtype believed to play a more pivotal role in neurodegeneration, has not rnbeen tested in MS. In this study inhibition of NR2B-containing NMDAR was evaluated on ...